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Estimated intraoperative blood loss of more than 1 L occurred in 7.3 and 8.0 percent of those in the tranexamic acid and placebo groups, respectively (relative risk, 0.91; 95 percent confidence interval, 0.79 to 1.05).
Interventions for bleeding complications occurred in 16.1 and 18.0 percent of those in the tranexamic acid and placebo groups, respectively (relative risk, 0.90; 95 percent confidence interval, 0.82 to 0.97).
"Prophylactic administration of tranexamic acid during cesarean delivery did not lead to a lower risk of maternal death or blood transfusion," the authors write.