ABSK112 is a leading next-generation EGFR Exon20ins inhibitor with improved selectivity over wild-type EGFR and strong brain penetrating ability.

Source: https://www.prnewswire.com/news-releases/abbisko-presents-the-research-results-of-5-programs-at-the-2023-aacr-annual-meeting-301797704.html

Enabled by HotSpot's proprietary Smart AllosteryTM platform, HST-1011 is designed with tight binding, low nanomolar potency, a slow dissociation rate from the target to enable sustained pharmacology, and greater selectivity for CBL-B relative to C-CBL.

Source: https://www.prnewswire.com/news-releases/hotspot-therapeutics-to-present-two-poster-presentations-on-cbl-b-program-at-aacr-annual-meeting-2023-301772058.html

In a scathing address of his own to the council, the Palestinian Authority’s minister of foreign affairs, Riyad al-Maliki, accused the international community of “selectivity and double standards.”

Source: https://www.nytimes.com/2023/10/24/world/middleeast/israel-gaza-bombing-un.html

Medicinal chemists work to modify the chemical structure of the leads to improve their potency, selectivity, and drug-likeness.

Source: https://cascadebusnews.com/upstream-development-in-biotech-unlocking-the-potential-for-therapeutic-breakthroughs/?utm_source=rss&utm_medium=rss&utm_campaign=upstream-development-in-biotech-unlocking-the-potential-for-therapeutic-breakthroughs

The breakthrough was made during early experiments which tested the compound both in vitro and in vivo, with data suggesting its in-vitro potency and selectivity to target, as well as its in-vivo availability in blood, shows excellent drug-like potential.

Source: https://www.alloaadvertiser.com/news/national/23665008.pills-made-cannabis-compound-help-treat-tumours/?ref=rss