A panel of US regulatory advisers said phenylephrine, a main component of over-the-counter cold including some versions of Procter & Gamble Co.’s Nyquil, doesn’t actually work.

Source: https://www.dailybreeze.com/2023/09/12/common-nasal-decongestant-doesnt-actually-work-fda-experts-say/

If the FDA follows through on the panel's recommendations, Johnson & Johnson, Bayer and other drugmakers could be required to pull their oral medications containing phenylephrine from store shelves.

Source: https://abc13.com/cold-medicine-fda-nasal-congestion/13773009/

It works in a similar way to phenylephrine, but is stronger and has an additional stimulant effect — so if you're tired and run down, it'll give you an energy boost (don't take this before bed).

Source: https://www.dailymail.co.uk/health/article-12559009/cold-flu-blocked-nose-winter-sickness.html?ns_mchannel=rss&ns_campaign=1490&ito=1490

The FDA has not asked pharmacies to remove the drugs, the Journal noted, but appears on track to ultimately remove phenylephrine from its list of approved medicines.

Source: https://www.wonkette.com/p/cvs-will-no-longer-sell-decongestant