Contrary to substance abuse, which bonds with the brain and impairs behavior control due to neurotoxicity, non-substance abuse is more of a mentality.

Source: https://eccunion.com/news/2023/04/14/likes-to-dislikes-the-social-media-addiction-epidemic/

GC012F also continued to show a favorable safety profile with around 78% patients not having CRS of any grade and no patients reporting neurotoxicity or icons.

Source: https://seekingalpha.com/article/4651389-gracell-biotechnologies-inc-grcl-q3-2023-earnings-call-transcript?source=feed_all_articles

Overstimulating the immune system like this can lead to potentially fatal side effects such as cytokine release syndrome (CRS) or neurotoxicity.

Source: https://www.forbes.com/sites/williamhaseltine/2023/06/27/the-future-of-cancer-treatment-treating-multiple-myeloma-with-mrna-car-t-technology/