And it also has a mix of monotherapy and adjunctive.

Source: https://seekingalpha.com/article/4603914-relmada-therapeutics-inc-rlmd-q1-2023-earnings-call-transcript?source=feed_all_articles

‘AOH1996 can suppress tumor growth as a monotherapy or combination treatment in cell and animal models without resulting in toxicity.

Source: https://metro.co.uk/2023/08/01/cancer-cure-pill-treatment-scientists-19228101/

CAPLYTA is the only U.S. Food and Drug Administration (FDA) approved treatment for depressive episodes associated with bipolar I or II disorder (bipolar depression) in adults as monotherapy and as adjunctive therapy with lithium or valproate.

Source: https://forextv.com/top-news/intra-cellular-therapies-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-corporate-update/

In another update, Affimed revealed its plans to debut initial data from two expansion cohorts of the AFM24 monotherapy study at the upcoming ASCO meeting.

Source: https://seekingalpha.com/article/4609244-affimeds-q1-2023-analysis-financial-and-regulatory-challenges-persist?source=feed_all_articles

The Phase 2 portion of the study is evaluating at the recommended dose from the Phase 1 monotherapy arm.

Source: https://www.marketscreener.com/quote/stock/BRISTOL-MYERS-SQUIBB-COMP-11877/news/Bristol-Myers-Squibb-Presents-New-Data-at-ASH-2023-Demonstrating-Clinical-Benefit-Across-B-cell-Mali-45538223/?utm_medium=RSS&utm_content=20231210

Your second question is really easy, doublet versus monotherapy.

Source: https://seekingalpha.com/article/4589748-aptose-biosciences-inc-apto-q4-2022-earnings-call-transcript?source=feed_all_articles