Because the gene that controls the expression of interferon gamma is on the X chromosome, it "escapes X inactivation in females" — meaning "there's more of it in females compared to males."

Source: https://www.salon.com/2023/03/22/why-do-fewer-women-of-covid-the-answer-could-lie-in-the-x-chromosomes-superpower/

How is type-1 interferon suppressed by the jab?

Source: https://www.lewrockwell.com/2023/01/joseph-mercola/shingles-activation-associated-with-covid-jab/

Infected cells sense the presence of the foreign genome and send a signal, in the form of an interferon molecule, to as yet uninfected cells.

Source: https://phys.org/news/2023-04-mechanisms-infections-influenza-ebola-viruses.html

The new treatment involves a single dose of pegylated interferon lambda, a synthetic version of a naturally occurring protein that infected cells secrete to defend against viral infection.

Source: https://northdenvernews.com/covid-treatment-shows-encouraging-results-in-trial-study-says/