Shift to In Vivo Editing: Secondly, they are recalibrating their research focus toward in vivo editing therapies.

Source: https://seekingalpha.com/article/4660193-editas-medicine-pivot-from-crispr-to-programmable-gene-editing?source=feed_all_articles

The authors indicate that the abnormal gene expression profile of extra-embryonic lineages (TE and PrE) of blastoids might be the major cause of their abnormal in vivo development.

Source: https://phys.org/news/2023-02-generation-blastocyst-like-spliceosomes-represses-mouse.html

The breakthrough was made during early experiments which tested the compound both in vitro and in vivo, with data suggesting its in-vitro potency and selectivity to target, as well as its in-vivo availability in blood, shows excellent drug-like potential.

Source: https://www.alloaadvertiser.com/news/national/23665008.pills-made-cannabis-compound-help-treat-tumours/?ref=rss

The studies, conducted in vitro in multiple cancer cell lines and in vivo in several pre-clinical cancer models, demonstrated the intended mechanism of action and high-level anti-cancer activity for these new molecules.

Source: https://www.marketscreener.com/quote/stock/MAIA-BIOTECHNOLOGY-INC-141660673/news/MAIA-Biotechnology-Reports-Full-Year-2022-Financial-Results-and-Provides-Corporate-Update-43333783/?utm_medium=RSS&utm_content=20230324