The patch fixes issues with specific quests, improves gameplay with the addition of the Arm cyberware to the weapon cycling sequence, and makes the Trauma Drama mini-game more challenging.

Source: https://gamerant.com/cyberpunk-2077-update-patch-notes-2-01/

Users who implant too much cyberware can suffer from a condition called cyberpsychosis, which negatively affects their minds and can result in them eventually becoming mindless killing machines.

Source: https://gamerant.com/cyberpunk-2077-phantom-liberty-dlc-cyberware-risk-psychosis/