Havoc suffers a near-death experience at the hands of Homunculi Lust, his former girlfriend, resulting in him not being able to walk again.

Source: https://gamerant.com/most-underrated-characters-in-fullmetal-alchemist-brotherhood/

While no new anime projects have been confirmed for the franchise, the Elric Brothers and the Homunculi recently returned thanks to the live-action movie trilogy that retold the story that had spawned from the mind of creator Hiromu Arakawa.

Source: https://comicbook.com/anime/news/fullmetal-alchemist-cosplay-lust-best-anime-girl/